A longstanding prohibition in the Americans with Disabilities Act disallows claims under the Act arising from “transsexualism” or “gender identity disorder.” With the removal of GID and the introduction of the separate and distinct diagnosis of “gender dysphoria” in the DSM-V, however, actions arising from discrimination against people on the basis of their real or perceived transgender status are back on the table. Some are reluctant to pursue this type of case, however, on the grounds that it is inappropriate to claim gender dysphoria as a disability. Are these concerns based on ableism, or are there meaningful legal reasons to resist that association? Our panel of experts on ADA litigation will give an overview of the history of ADA litigation on the basis of gender dysphoria, the process for bringing such a claim, and the advantages and disadvantages of seeking a redress of harm under the ADA rather than under other nondiscrimination laws. We will also discuss stigmas and the destigmatization of bringing actions under the ADA.