GLMA (a national organization committed to ensuring health equity for LGBTQ+ people and equality for LGBTQ+ health professionals) and 16 impacted health researchers are challenging the National Institutes of Health’s (NIH) termination of hundreds of grants funding important research on issues regarding HIV and LGBTQ+ people’s health. Following the Trump Administration’s issuance of three executive orders targeting the LGBTQ+ community and government programs supporting the LGBTQ+ community and other strategically devalued communities, NIH cancelled or substantially reduced over 300 grants supporting research into understanding and improving the health of LGBTQ+ and HIV positive people. Plaintiffs argue these cancellations and reductions, based upon policy implemented in response to the Trump Administration’s executive orders, violate the Administrative Procedure Act, the Affordable Care Act, the Fifth Amendment of the U.S. Constitution, and the Due Process Clause.